Friday, March 4, 2016

Kidney transplantation in children with congenital anamolies: improved outcomes

Congenital uropathy included chronic pyelonephritis/reflux, prune belly syndrome and congenital obstructive uropathy. Congenital pediatric kidney disease included polycystic kidney disease, hypoplasia, dysplasia, dysgenesis, agenesis and familial nephropathy.

Analysis of trends in the last 14 years in SRTR (Scientific Registry of Transplant Recipients)demonstrates that patients with both lower and upper tract congenital anomalies experienced delayed time to the first renal transplant. Furthermore, patients had similar age matched graft and patient survival whether the primary source of renal demise was the congenital lower or upper tract. These findings may indicate that improved urological and nephrological care are promoting renal preservation in both groups.

Encouraging indeed! 

Take home message: 
Important to screen CAKUT and manage them well early to prevent renal deterioration. 


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