Sunday, May 8, 2016

CME Live: Anticoagulation

CME Live: Anticoagulation

Dr. Rupesh Raina

Curofy- India's largest community of verified doctors covered the CME-International Neonatal and Pediatric Nephrology Training Workshop live. This post was first published on the Curofy app. 

Heparin:

Commonly used
Easy to use and monitor
No evidence on dose
Systemic side effect
Contraindicated in bleeding patient

Citrate

Calcium dependent mechanism 
Binds to free calcium and inhibits binding
Has zero effect upon the patient 
Easy to monitor
Less clotted circuits
Less work of machinery

Problems:

Metabolic alkalosis
Electrolyte disorders
Cardiac toxicity

Complications: 
Seen with rising total calcium with dropping patient ionized calcium.
Citrate gap.


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